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. 2014 Mar 30;20(5):748–758. doi: 10.1093/humupd/dmu012

Table III.

Findings of the present meta-analysis of 11 studies, with subgroup analysis based on age of the women (over or under age 54 years).

Disease site Studies included in analysis Number of studies Odds ratio (95% confidence interval) Z χ2 I2
Endometrial cancer All endometrial cancer studies 5 2.79 (1.31–5.95) 2.65 (P < 0.008) 11.33 (P < 0.02) 65%
Excluding samples that included women over age 54 years (Zucchetto et al., 2009) 4 4.05 (2.42–6.76) 5.34 (P < 0.00001) 0.65 (P < 0.88) 0%
Ovarian cancer All ovarian cancer studies 3 1.41 (0.93–2.15) 1.62 (P < 0.11) 2.39 (P < 0.30) 16%
Excluding samples that included women over age 54 years (Olsen et al., 2008; Bodmer et al., 2011) 1 2.52 (1.08–5.89) 2.14 (P < 0.03) n/a n/a
Breast cancer All breast cancer studies 3 0.95 (0.64–1.39) 0.27 (P < 0.78) 1.42 (P < 0.06) 0%
Excluding samples of women over age 54 years (Anderson et al., 1997) 2 0.78 (0.46–1.32) 0.93 (P < 0.35) 0.26 (P < 0.61) 0%