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. 2014 Aug 18;24(1):265–273. doi: 10.1093/hmg/ddu420

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Figure 1. — Regional association plots for three loci with genome-wide significant or suggestive associations with LSLs. Each pane: (A) rs1975649 (B) rs11008222 (C) rs8061121, shows the association statistic (−log₁₀ P for the likelihood ratio test) from Stage 1 for the variant (diamond) and nearby markers (squares) on the left y-axis. The red shading indicates linkage disequilibrium (r²) between the variant and nearby markers. The light blue lines indicate recombination rates across each region in 1000 Genomes Pilot 1 CEU data (right y-axis). Chromosome position (hg18) and nearby genes are shown on the x-axis.

Figure 1. — Regional association plots for three loci with genome-wide significant or suggestive associations with LSLs. Each pane: (A) rs1975649 (B) rs11008222 (C) rs8061121, shows the association statistic (−log₁₀ P for the likelihood ratio test) from Stage 1 for the variant (diamond) and nearby markers (squares) on the left y-axis. The red shading indicates linkage disequilibrium (r²) between the variant and nearby markers. The light blue lines indicate recombination rates across each region in 1000 Genomes Pilot 1 CEU data (right y-axis). Chromosome position (hg18) and nearby genes are shown on the x-axis.