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Icariin increased Bcl-2 protein levels in PC12 cells exposed to Aβ 25–35. After pretreatment with 50 μM LY294002 for 1 h, PC12 cells were treated with 20 μM icariin for 1 h, followed by 24 h Aβ 25–35 treatment. Densitometry values are presented as mean ± S.D. of triplicate independent experiments. ## P < 0.01 versus control; ** P < 0.01 versus Aβ 25–35 treatment; $$ P < 0.01 versus icariin treatment.
