Table 4.
Significantly enriched KEGG pathways of downregulated genes (fold change ≥3-fold)
| Term | No. of genes | Genes | P value | Fold enrichment |
|---|---|---|---|---|
| bta04810, regulation of actin cytoskeleton | 8 | FGF7, CHRM3, ROCK1, ROCK2, PPP1R12A, PIK3CA, ITGB1, PIK3R1 | 0.00914 | 3.30 |
| bta04350, TGF-β signaling pathway | 5 | SP1, ROCK1, ROCK2, ZFYVE16, BMPR1A | 0.01676 | 4.96 |
| bta04510, focal adhesion | 7 | ROCK1, ROCK2, PPP1R12A, PIK3CA, BIRC3, ITGB1, PIK3R1 | 0.02562 | 3.02 |
| bta05200, pathways in cancer | 9 | FGF7, HIF1A, PIK3CA, PTCH2, TPR, BIRC3, ITGB1, MMP1, PIK3R1 | 0.03423 | 2.33 |