Table 4.

Haplotype frequencies of miR-146a C > G, miR-149 T > C, miR-196a2 T > C and miR-499 T > C SNPs in the Southern Han population

Haplotype	Allele at marker				Controls N (Freq)	Patients N (Freq)	Total N (Freq)	OR (95% CI)	P value
	miR-499	miR-196a2	miR-146a	miR-149
1	T	C	C	T	0.1639	0.1699	0.1643	1.00	---
2	T	T	G	T	0.1491	0.1689	0.1487	0.96 (0.51 - 1.79)	0.9
3	T	T	C	T	0.1266	0.136	0.1378	0.67 (0.27 - 1.65)	0.38
4	T	T	C	C	0.0662	0.1378	0.0953	2.33 (0.98 - 5.55)	0.057
5	T	T	G	C	0.0761	0.0697	0.0828	0.60 (0.24 - 1.50)	0.27
6	T	C	G	T	0.0926	0.0533	0.0796	0.35 (0.10 - 1.19)	0.092
7	T	C	G	C	0.0711	0.0736	0.0652	0.95 (0.38 - 2.36)	0.91
8	T	C	C	C	0.0607	0.0358	0.053	0.23 (0.05 - 0.96)	0.044
9	C	T	G	T	0.0384	0.0174	0.0366	0.24 (0.04 - 1.37)	0.11
10	C	C	C	T	0.0325	0.0065	0.0303	0.03 (0.01 - 0.63)	0.024
11	C	T	C	T	0.0182	0.0365	0.0211	3.38 (0.54 - 21.22)	0.19
12	C	C	C	C	0.0333	0.0188	0.0194	0.42 (0.04 - 4.04)	0.45
13	C	C	G	C	0	0.0244	0.0189	0.00 (-Inf - Inf)	1
14	C	T	G	C	0.0457	0	0.0181	0.00 (-Inf - Inf)	1
15	C	T	C	C	0.0052	0.017	0.0158	1.41 (0.02 - 90.56)	0.87
16	C	C	G	T	0.0203	0.0344	0.0131	1.35 (0.19 - 9.60)	0.76
Global haplotype association P-value: 0.0084

Freq: frequency of haplotype, OR: odds ratio, N: number of subjects, CI: confidence interval.