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. 2015 Feb 12;10(2):e0117546. doi: 10.1371/journal.pone.0117546

Fig 6. Potential structural consequences of S-nitrosylation for PCNA.

Fig 6

(A) The surface accessibility of S-nitrosylation sites. The sulfhydryl group (yellow) of Cys81 was exposed at the protein surface (left), but that of Cys162 was buried inside (right). (B) Molecular simulations of wild-type and SNOC-modified PCNAs. S-nitrosylation at Cys81 clearly affected the local structure of this residue, which may interfere with the interactions, but the Cys162 modification had no significant influence on the structure.