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. 2015 Feb 5;16(1):40. doi: 10.1186/s12864-015-1279-9

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© Polioudakis et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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miR-503 involvement in breast cancer. (A) Low miR-503 expression correlates with a lower survival probability in ER+ breast cancer patients (p = 8.56e-06). Kaplan-Meier survival curves for patients with ER+ breast cancer expressing different levels of miR-503 were calculated using the MIRUMIR tool. Number of patients: n = 37. (B) DDHD2 is frequently amplified in breast cancer. The bars are the frequency of DDHD2 copy number alterations in the different types of cancer indicated on the X-axis. The frequency of patients with DDHD2 amplification was calculated using the cBio portal. Yellow: Deletion; Orange: Amplification. n = 1044. (C) Patients with copy number alterations in DDHD2 (purple line) have a lower survival probably than those without amplifications in DDHD2 (green line) (p = 0.027). Kaplan-Meier survival curves were was calculated using the cBio portal. n = 888.