Table 1.
Uncomplicated* P. falciparum malaria ( n = 5 ) | Complicated P. falciparum malaria ( n = 20 ) | |
---|---|---|
Age | 28 | 29 |
Gender (male: female) | 5:0 | 12:8 |
Days of fever (p = 0.41) | 3.6 ± 0.98 | 4.45 ± 0.44 |
Admission parasite count/μL (p = 0.51) | 52,638 ± 12,990 | 181,315 ± 55,314 |
WBC (×109/L) (p = 0.041) | 5.82 ± 1.24 | 9.61 ± 0.79 |
Hb (g/dL) (p = 0.17) | 12.70 ± 1.35 | 11.10 ± 0.56 |
Platelets (×109/L) (p = 0.20) | 50.60 ± 7.98 | 70.85 ± 28.69 |
BUN (ml/dL) (p = 0.51) | 24.84 ± 4.86 | 34.96 ± 5.70 |
Creatinine (ml/dL) (p = 0.73) | 1.06 ± 0.11 | 2.21 ± 0.70 |
TB (mg/dL) (p = 0.01) | 1.91 ± 0.34 | 5.88 ± 1.14 |
DB (mg/dL) (p = 0.0073) | 0.56 ± 0.23 | 3.34 ± 0.80 |
AST (IU/L) (p = 0.0012) | 25.40 ± 3.56 | 112.0 ± 21.50 |
ALT (IU/L) (p = 0.0039) | 21.80 ± 5.23 | 90.85 ± 15.19 |
*Clinical data available for 5 uncomplicated P. falciparum malaria patients.
WBC-white blood cell count, Hb-haemoglobin, BUN-blood urea nitrogen, TB-total bilirubin, DB-direct bilirubin, AST-aspartate aminotransferase, ALT-alanine aminotransferase. Data expressed as mean ± SEM.