Table 1.
Day | 0.4% NaCl Control | HS-7 | HS-14 | HS-21 | ||||
---|---|---|---|---|---|---|---|---|
Group | WT | SSp67phoxNull | WT | SSp67phoxNull | WT | SSp67phox Null | WT | SSp67phox Null |
Creatinine Clearance (ml/min/100g bw) | 0.84±0.04 | 0.89±0.06 | 1.13±0.05‡ | 1.07±0.05* | 1.08±0.02† | 1.08±0.04 | 1.00±0.06 | 0.96±0.08 |
Creatinine Clearance is not reflective of GFR in either wild-type (WT) or SSp67phox null rats. Creatinine clearance was compared on a 0.4% NaCl control day and 4.0% NaCl day-7 (HS-7), day-14 (HS-14) and day-21 (HS-21). bw indicates body weight.
p<0.05,
p<0.01,
p<0.001 compared to control measurements.