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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Hypertension. 2014 Dec 15;65(3):587–593. doi: 10.1161/HYPERTENSIONAHA.114.04681

Figure 3.

Figure 3

Effect of a c-Met antagonist on intracranial aneurysm formation and rupture in mice. (A) Cerebral arteries and intracranial aneurysm in situ (left) and after dissection (right). Note the hemorrhage surrounding the aneurysm. Survival (B), systolic blood pressure (C), weight loss (D), aneurysm formation (E) and prevalence of subarachnoid hemorrhage (F) in sham controls (n=5), and after induction of aneurysms in mice treated with PF-04217903 (n=16) or vehicle (n=14). *=p<0.05 vs sham; ψ=P<0.05 vs baseline. ϕ=P<0.05 vs. vehicle.