Table I.
Clinical benefit in patients with sunitinib dose-escalation
| SUNITINIB DOSE ESCALATION FROM 50 MG DOSE |
ADDED PFS AFTER DOSE ESCALATION |
|---|---|
| 62.5 mg | 11 months |
|
| |
| 62.5 mg | 10 months |
|
| |
| 62.5 mg | 8 months |
|
| |
| 62.5 mg | 16 months & currently ongoing |
|
| |
| 62.5 mg | 6 months |
|
| |
| 62.5 mg | 5 months |
| 75 mg | 15 months |
|
| |
| 62.5 mg | 3 months |
| 75 mg | 3 weeks |
|
| |
| 62.5 mg | 2 months |
|
| |
| 62.5 mg | 2 months |
|
| |
| 62.5 mg | 5 months |
|
| |
| 62.5 mg | 2 months |
| 75 mg | 5 months |
|
| |
| 62.5 mg | 1 months |
| 75 mg | 17 months & currently ongoing |
|
| |
| 75 mg | 24 months & currently ongoing |
|
| |
| 75 mg | 21 months |
|
| |
| 75 mg | 4 months |
|
| |
| 75 mg | 2 months |