Table 5.

GO and KEGG pathway analysis for differentially expressed genes with SNPs and putative miRNA targets

Term	P-value	Benjamini
GO molecular function
GO:0004672 ~ protein kinase activity	1.61E–10	1.52E–07
GO:0004713 ~ protein tyrosine kinase activity	1.71E–07	8.10E–05
GO:0001883 ~ purine nucleoside binding	2.99E–07	9.43E–05
GO:0030554 ~ adenyl nucleotide binding	4.05E–07	9.57E–05
GO:0001882 ~ nucleoside binding	4.37E–07	8.26E–05
GO biological process
GO:0006796 ~ phosphate metabolic process	6.73E–12	2.30E–08
GO:0006793 ~ phosphorus metabolic process	6.73E–12	2.30E–08
GO:0042127 ~ regulation of cell proliferation	1.12E–09	1.91E–06
GO:0022403 ~ cell cycle phase	4.51E–09	5.14E–06
GO:0009725 ~ response to hormone stimulus	5.94E–09	5.08E–06
GO cellular component
GO:0031012 ~ extracellular matrix	5.41E–06	0.002361673
GO:0000793 ~ condensed chromosome	8.42E–06	0.001838134
GO:0005604 ~ basement membrane	1.32E–05	0.00192431
GO:0005578 ~ proteinaceous extracellular matrix	1.70E–05	0.001851468
GO:0005829 ~ cytosol	7.08E–05	0.006167834
KEGG pathway
hsa05200:Pathways in cancer	5.53E–13	1.00E–10
hsa04110:Cell cycle	8.05E–05	0.007254812
hsa05222:Small-cell lung cancer	8.89E–05	0.005350669
hsa00330:Arginine and proline metabolism	0.001255698	0.055269935
hsa04510:Focal adhesion	0.001294948	0.045824355

Abbreviations: GO, gene ontology; miRNA, microRNA; SNP, single-nucleotide polymorphism. Only top five terms in each category are shown.