Fig. 3. A schematic overview of structure of CTGF and factors interacting with CTGF.

BMP, bone morphogenic protein; Cys-knot, cystine knot; ECM, extracellular matrix ; HSPG, heparan sulfate proteoglycan; IGF-1, insulin like growth factor-1; LRP, lipoprotein receptor–related protein; TGF-β1, transforming growth factor-β1; VEGF, vascular endothelial growth factor ; vWF, von Willebrand factor.