Table 2.
Relationship of Maximum Daily Score With Weekly Score
| % Weeks With a Daily Score ≥1 |
Mean (SD) Weekly Score |
Mean (SD) Maximum Daily Score |
Mean Difference (Weekly-Max Daily) |
Effect Size |
CCC | |
|---|---|---|---|---|---|---|
| Fatigue | 86% | 1.42 (0.91) | 1.77 (1.05) | −0.35 | 0.35 | 0.709 |
| Insomnia | 76% | 1.15 (0.91) | 1.42 (0.98) | −0.27 | 0.28 | 0.767 |
| Appetite | 70% | 1.23 (1.07) | 1.49 (1.19) | −0.25 | 0.22 | 0.834 |
| Dry Skin | 67% | 0.90 (0.78) | 1.07 (0.83) | −0.17 | 0.21 | 0.816 |
| Itchy Skin | 52% | 0.64 (0.70) | 0.87 (0.81) | −0.23 | 0.30 | 0.659 |
| Pain | 52% | 0.86 (1.01) | 1.07 (1.11) | −0.21 | 0.20 | 0.808 |
| Nausea | 46% | 0.71 (0.94) | 0.97 (1.21) | −0.26 | 0.22 | 0.787 |
| Stools | 46% | 0.75 (1.02) | 1.02 (1.18) | −0.27 | 0.24 | 0.764 |
| Concentration | 46% | 0.50 (0.59) | 0.68 (0.78) | −0.18 | 0.25 | 0.625 |
| Anxiety | 42% | 0.53 (0.72) | 0.73 (0.87) | −0.2 | 0.24 | 0.670 |
| Shortness of Breath | 41% | 0.50 (0.69) | 0.62 (0.77) | −0.12 | 0.17 | 0.762 |
| Rash | 40% | 0.47 (0.64) | 0.68 (0.84) | −0.2 | 0.25 | 0.737 |
| Memory | 40% | 0.47 (0.65) | 0.58 (0.76) | −0.11 | 0.15 | 0.801 |
| Abdominal Pain | 35% | 0.50 (0.78) | 0.70 (0.95) | −0.2 | 0.23 | 0.773 |
| Dizziness | 32% | 0.35 (0.54) | 0.47 (0.65) | −0.12 | 0.20 | 0.632 |
| Headache | 29% | 0.39 (0.71) | 0.53 (0.83) | −0.14 | 0.18 | 0.734 |
| Sad/Unhappy Feelings | 28% | 0.39 (0.73) | 0.61 (0.91) | −0.22 | 0.26 | 0.643 |
| Mouth Sores | 28% | 0.54 (1.00) | 0.73 (1.17) | −0.18 | 0.16 | 0.834 |
| Chills | 25% | 0.33 (0.68) | 0.53 (0.87) | −0.21 | 0.26 | 0.513 |
| Cough | 19% | 0.24 (0.56) | 0.34 (0.70) | −0.1 | 0.15 | 0.782 |
| Constipation | 18% | 0.24 (0.59) | 0.48 (0.87) | −0.24 | 0.30 | 0.563 |
Symptoms are ranked by the percentage of weeks in the study during which there was at least one daily score of ≥1 for that symptom during that week. Means and standard deviations of both weekly and daily maximums are given, along with the effect size, to allow comparisons across symptoms. The negative numbers for the mean difference between weekly and daily maximums scores indicate the daily maximums scores were most often higher. The concordance correlation coefficient (CCC) shows the strength of the correlation between the maximum daily scores and weekly scores. A CCC of 0 demonstrates no correlation, and a CCC of +1 demonstrates perfect correlation.