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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Addict Biol. 2014 Aug 13;21(1):35–48. doi: 10.1111/adb.12174

Figure 3. Activation of D2 receptors similarly inhibits evoked firing of NAc MSNs from Dbh +/− and C57BL/6J mice.

Figure 3

Example traces of a MSN from a Dbh +/− (a) and a wild-type C57BL/6J (b) animal at baseline and following bath application of the D2/3 agonist, quinpirole (5 μM), while action potentials were evoked with a series of current steps. Dashed line indicates −70 mV. (c) Population data (mean ± SEM) showing the effects of D2 receptor activation on spike frequency differences (quinpirole – baseline) from cells recorded from Dbh +/− (n = 22) and C57BL/6J (n = 24) mice.