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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Addict Biol. 2014 Aug 13;21(1):35–48. doi: 10.1111/adb.12174

Figure 4. Quinpirole inhibits evoked firing of NAc MSNs from control, but not Dbh −/− mice.

Figure 4

Example traces of a MSN from a control (a) and Dbh −/− (b) animal at baseline, and following bath application of the D2/3 agonist, quinpirole (5 μM), while action potentials were evoked with a series of current steps. Dashed line indicates −70 mV. (c) Population data (mean ± SEM) showing the effects of D2-like receptor activation on evoked spike frequency differences (quinpirole – baseline) from cells recorded from control (n = 46) and Dbh −/− (n = 15) mice. * indicates significant difference (p < 0.05) between control and Dbh −/− population data.