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. 2014 Dec 4;290(7):3964–3971. doi: 10.1074/jbc.R114.581249

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FIGURE 2. — SPASM/Twitch subfamily reactions. The involvement of SPASM/Twitch domain containing enzymes, anSME, MoaA, BtrN, and AlbA/SkfB in the biosynthesis of their respective products is shown. The specific reaction catalyzed by SPASM enzyme PqqE is not indicated as its substrate is not known. For AlbA, only one of the three thioether bond formations is shown. Hydrogen atoms known or proposed to be abstracted by the 5′-deoxyadenosyl radical are shown in blue. DOIA, 2-deoxy-scyllo-inosamine; amino-DOI, 3-amino-2,3-dideoxy-scyllo-inosose.