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. 2014 Dec 30;290(7):4464–4475. doi: 10.1074/jbc.M114.613497

TABLE 2.

Affinities of 2-AP for wild-type and mutant pbuE aptamer domains

RNA KD(app) (nm) KD(rel)a
Wild-type 300 ± 30 1.0
U66C 200,000 ± 10,000 660
G52C,G53C ND
A48U 2700 ± 300 9.2
U49A 880 ± 90 3.0
A50U 720 ± 120 2.4
U51G 870 ± 90 2.9

a KD(rel) = KD(app)(mutant)/KD(app)(WT); ND, not detectable.