Table 1. Selected drugs associated with acute interstitial nephritis (AIN).
Antibiotics | β-lactam drugs* |
Fluoroquinolones* | |
Rifampin* | |
Sulfa-based drugs* | |
Vancomycin | |
Minocycline | |
Ethambutol | |
Erythromycin | |
Chloramphenicol | |
Antiviral medications | Acyclovir |
Abacavir | |
Indinavir | |
Atazanavir | |
GI medications | Proton pump inhibitors* |
Histamine-2 receptor blockers | |
Analgesics | Nonsteroidal anti-inflammatory drugs* |
Selective COX-2 inhibitors | |
Anti-seizure drugs | Phenobarbital |
Phenytoin* | |
Carbamazepine | |
Other drugs | Allopurinol* |
5-Aminosalicylates* | |
Captopril | |
Interferon | |
Cyclosporine | |
Anti-angiogenesis drugs (tyrosine kinase inhibitors) | |
Diuretics |
*Most common offending agents.