Table 2. Evaluation of eosinophiluria in diagnosis of acute interstitial nephritis (AIN).
| Reference | Patients | Sensitivity | Specificity | Other diagnoses |
|---|---|---|---|---|
| Nolan et al. [30] | N = 92 Hansel stain |
10/11 (91%) | 69/81 (85%) | ATN (0/30) Pyn (0/10) GN (1/6) RPGN (4/10) Prostatitis (6/10) |
| Corwin et al. [31] | N = 183 Hansel stain |
5/8 (63%) | 160/175 (93%) | ATN (1/29) UTI (4/37) DN (4/17) |
| Ruffing et al. [32] | N = 51 Hansel stain |
6/15 (40%) | 26/36 (72%) | GN (4/6) CKD (2/5) Pyn (1/2) |
| Total | 326 | 21/34 (62%) | 255/292 (87%) |
AIN = acute interstitial nephritis; Eos = eosinophils; UTI = urinary tract infection; CIN = contrast-induced nephrotoxicity; CKD = chronic kidney disease; Pyn = pyelonephritis; GN = glomerulonephritis; RPGN = rapidly progressive glomerulonephritis; ATN = acute tubular necrosis; DN = diabetic nephropathy.