Table 3.

(a) Samples with 2 or more mutations in both complex I and III; (b) samples with 2 or more mutations in both complex I and V

Population (n. total sample)	n. sample	%
(a)
Denmark controls (429)	131	30.53
inland controls (166)	32	21.91
South Europe controls (71)	28	39.43
Total controls (666)	191	28.67*
Denmark 90+ (423)	117	27.66
Finland 90+ (148)	23	15.54
South Europe 90+ (75)	22	18.66
Total 90+(646)	162	25.07*
(b)
Denmark controls (429)	55	12.82
Finland controls (166)	17	10.24
South Europe controls (71)	13	18.31
Total Controls (666)	85	12.76†
Denmark 90+ (423)	39	9.22
Finland 90+ (148)	11	7.43
South Europe 90+ (75)	7	9.33
Total 90+(646)	57	8.82†

^*The co-occurrence of two or more mutations in complex I and III is more frequent in controls than in 90+ (P = 0.03).

^†The co-occurrence of two or more mutations in complex I and V is more frequent in controls than in 90+ (P = 0.02).