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. 2014 Aug 12;39(2):312–320. doi: 10.1038/ijo.2014.122

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Cardiometabolic profile of HFD-induced obese mice. (a) Glucose tolerance test (GTT) in mice after 18 weeks of exposure to ND (n=8) or HFD (n=10). (b) Interventricular septum thickness (IVST), (c) LV posterior wall thickness (LVPWT) and (d) fractional shortening (FS) and (e) ejection fraction (EF) were analyzed by two-dimensional guided M-mode echocardiography in ND-fed and HFD-fed mice. (f) Real-time reverse transcriptase (RT)-PCR analysis of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) expression levels in heart tissue from ND-fed (n=6) and HFD-fed (n=7) mice. (g) Myocardial FA oxidation and (h) glucose oxidation in ND-fed (n=7) and HFD-fed (n=8) mice. Results are means±s.e.m. **P<0.01; ***P<0.001 vs ND.