Table 1. Metabolic parameters in mice under ND and HFD feeding.

	ND	HFD
Body weight (g)	31.5±1.1	44.8±0.7***
Fat mass (%)	14.1±0.9	38.8±1.2***
Glucose (mM)	7.9±0.2	10.3±0.8*
Insulin (pg ml–1)	1364.7±51.0	3753.3±54.8**

Abbreviations: HFD, high-fat diet; ND, normal diet.

Male C57BL/6J mice were fed ND or HFD for 18 weeks. Body weight, fat mass and plasma parameters were measured at the end of week 4. Data are means±s.e.m.; n=8 per group. *P<0.05 vs ND-fed group; **P<0.01 vs ND-fed group; ***P<0.001 vs ND-fed group.