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. 2015 Feb 13;9:8. doi: 10.3389/fnsys.2015.00008

Table 1.

Anatomical evidence for direct projections and their neurotransmitters.

Projection Origin of evidence Neurotransmitters used Origin of evidence
pfLH → AcbSh, lLH → AcbSh Phillipson and Griffiths (1985), Brog et al. (1993), Kampe et al. (2009), Hahn and Swanson (2010) Orexin, MCH* Bittencourt et al. (1992), Trivedi et al. (1998), Saito et al. (2001), Baldo et al. (2003), Kampe et al. (2009)
vlLH → pAcbSh Phillipson and Griffiths (1985), Brog et al. (1993), Goto et al. (2005) GABA Vong et al. (2011)
pfLH → LS, lLH → LS Risold and Swanson (1997b) Orexin, MCH, CART* Bittencourt et al. (1992), Marcus et al. (2001), Saito et al. (2001), Baldo et al. (2003), Janzsó et al. (2010)
vlLH → LS Risold and Swanson (1997b) GABA Vong et al. (2011)
LS → AcbSh Brog et al. (1993), Zahm et al. (2013) GABA Zhao et al. (2013)
pfLH → PVT, lLH → PVT Chen and Su (1990), Kirouac et al. (2006), Hahn and Swanson (2010) Orexin, MCH, CART* Marcus et al. (2001), Saito et al. (2001), Baldo et al. (2003), Kirouac et al. (2006)
pfLH → PVT Otake and Nakamura (1995) CRF Otake and Nakamura (1995)
vlLH → PVT Chen and Su (1990) GABA Vong et al. (2011)
PVT → AcbSh Meredith and Wouterlood (1990), Brog et al. (1993), Parsons et al. (2006), Vertes and Hoover (2008), Ligorio et al. (2009) Glutamate Meredith and Wouterlood (1990), Ligorio et al. (2009)
pfLH → VP, lLH → VP Cullinan and Záborszky (1991), Hahn and Swanson (2010) Orexin* Baldo et al. (2003)
vlLH → VP Goto et al. (2005) GABA Vong et al. (2011)
VP → AcbSh Haber et al. (1985), Phillipson and Griffiths (1985), Brog et al. (1993) GABA Churchill and Kalivas (1994)

*Certain co-transmitters are assumed for specific neuron types. Specifically, orexin is co-transmitted with glutamate and dynorphin, MCH with GABA, and CART with GABA.