Fig. 1.

Boxplots of TIMP1 (a), NT-proBNP (b), CRP (c) and GFR (d) distributions and levels in the 3 study groups. All indices of cardiorenal dysfunction are elevated in the CHF patients in comparison with the 2 control groups. CRP shows a significant difference only between the CHF patients and the marathoners with AH. Median values and 25th-75th percentiles are indicated by horizontal and vertical lines, respectively. Significant differences (p value) between the groups are given in each graph.