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. 2015 Feb 13;5:8461. doi: 10.1038/srep08461

Figure 4. The ESCRT-III component shrub and accessory mop are required for axon and dendrite pruning.

Figure 4

(a) C161-GAL4 labels class I da sensory neurons ddaD and ddaE that undergo remodeling; at 24 h APF the dendrites of have been pruned. (b) In class I da neurons expressing shrub-RNAi, some dendritic branches have not been severed (arrow). (c) At 24 h APF class I da neurons expressing mop-RNAi still have intact dendritic branches. (d) At 24 h APF, the axons of mushroom body γ-neurons have been pruned to the node at which they branch (arrows). (e) In γ-neurons expressing a shrub-RNAi a large number of axons fail to prune by 24 h APF (arrows). (f) γ-neurons of the mushroom body expressing mop-RNAi fail to prune their axons by 24 h APF (arrows). Scale bar = 50 μm.