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. Author manuscript; available in PMC: 2015 Feb 13.
Published in final edited form as: Prog Mol Biol Transl Sci. 2010;95:237–298. doi: 10.1016/B978-0-12-385071-3.00009-5

Figure 13.

Figure 13

Representative functional diffusion map (fDM) analysis at 1, 3, and 10 weeks of clinically (left panels) responding and (right panels) non-responding patients to fractionated radiation therapy. Presented images are single slices of the T1-weighted contrast-enhanced scans at each time point with a pseudocolor overlay of the fDM. Red voxels indicate regions with a significant rise in apparent diffusion coefficient (ADC) at each time point compared with pretreatment, green regions had unchanged ADC, and blue voxels indicate areas of significant decline in ADC. The scatter plots display data for the entire tumor volume and not just for the depicted slice at each time point, with the pretreatment ADC on the x-axis and post-treatment ADC on the y-axis. The central red line represents unity, and the flanking blue lines represent the 95% CIs. (From [276], with permission.)