Table 4.
Multivariate regression: SP a -IPTp b doses (categorical variables) associated with outcomes of interest
| Adjusted model c | <2 vs ≥2 doses PR d (95% CI e ) | <3 vs ≥ 3 doses PR (95% CI) | 2 vs ≥3 doses PR (95% CI) |
|---|---|---|---|
| Placental infectionf | |||
| Paucigravid | 0.77 (0.58- 1.01) | 0.89 (0.64-1.23) | 1.06 (0.71-1.57) |
| Multigravid | 1.00 (0.66-1.52) | 0.87 (0.55-1.39) | 0.83 (0.49-1.39) |
| Low birth weight (<2,500 g) | |||
| Paucigravid | 0.33 (0.12-0.91) | 0.43 (0.10-1.81) | Could not compute |
| Multigravid | 0.51 (0.21-1.25) | 0.26 (0.06-1.11) | Could not compute |
| Preterm (<37 weeks) | |||
| Paucigravid | 0.93 (0.49-1.78) | 0.70 (0.34-1.44) | Could not compute |
| Multigravid | 0.28 (0.13-0.60) | 0.15 (0.04-0.55) | Could not compute |
| Composite birth outcomeg | |||
| Paucigravid | 1.09 (0.73-1.61) | 0.84 (0.54-1.31) | Could not compute |
| Multigravid | 0.50 (0.32-0.78) | 0.43 (0.24-0.80) | Could not compute |
| Any infectionh | |||
| Paucigravid | 0.76 (0.58-0.99) | 0.88 (0.65-1.21) | 1.06 (0.72-1.55) |
| Multigravid | 1.04 (0.69-1.58) | 0.86 (0.54-1.36) | 0.79 (0.48-1.33) |
aSP = sulphadoxine pyrimethamine.
bIPTp = intermittent preventive treatment for malaria in pregnancy.
c Model adjusted for: Age group (<18, 18–35, >35), gravidity as an interaction term, sleeping under an ITN the last night at home, living in a home treated with IRS, urban, facility, delivered during the wet season, marital status.
dPR = prevalence ratio.
eCI = 95% confidence interval.
fPlacental infection outcome: histopathology classes 1–4 vs class 5.
gComposite birth outcome defined as infants born with any of: LBW, SGA or preterm.
hAny infection defined as: pathology classes 1–4, blood smear positive (maternal, placental or cord blood).