Table 1.
DENV serotype c | Without MB21 | With MB21 d | P value e |
---|---|---|---|
1 | 1.06 ± 0.03 | 0.52 ± 0.02 | 0.0028*** |
2 | 1.54 ± 0.12 | 0.27 ± 0.01 | 0.0045*** |
3 | 0.59 ± 0.01 | 0.14 ± 0.04 | 0.0065*** |
4 | 0.22 ± 0.02 | 0.05 ± 0.03 | 0.031** |
aTiters were determined by plaque assay on Vero cells.
bPfu = plaque forming units.
cThe viral strains used were: DENV-1: West Pac 74; DENV-2: S-16803; DENV-3: CH54389; and DENV-4: TVP-360.
dMB21 used at 30 μM final concentration.
e P values were calculated using Graphpad software; P values were either significant (**) or very significant (***).