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. 2015 Feb 8;12:9. doi: 10.1186/s12950-015-0056-5

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© Elhai et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Mice deficient for DNAM-1 are not protected from collagen-induced arthritis at clinical assessment. (a) Examples of picture of clinical arthritis in paws from dnam1+/+ and dnam1−/− mice with redness and swelling of the paws involving tarsus, ankle and toes in both groups. Pictures were taken at day 54. 7 dnam1+/+ and 5 dnam1−/− mice were used. (b) Clinical score similarly increased in dnam1+/+ and dnam1−/− mice without significant difference. (c) Mean of the different clinical scores is not different between dnam1+/+ and dnam1−/− mice. (d) Maximal clinical score is similar in dnam1+/+ and dnam1−/− mice. Values are the median ± IQR.