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. Author manuscript; available in PMC: 2015 Oct 10.
Published in final edited form as: J Control Release. 2014 Jul 10;191:15–23. doi: 10.1016/j.jconrel.2014.07.003

Figure 2. Fusion of the L4F peptide depresses the ELP transition temperature.

Figure 2

Two ELPs of the same length and different transition temperatures were appended to L4F and observed using optical density as a function of temperature and concentration. A) Unmodified A192 phase separates near 60 °C. B) Addition of L4F to A192 depressed the transition temperature to about 45°C. C) Unmodified V2A192 phase separates around 47°C. D) Addition of L4F to V2A192 decreases the transition temperature to about 34°C. E–F) The concentration-temperature phase diagrams for all constructs follow a log-linear relationship. L4F suppressed both the magnitude and the slope (Table 1) of the line for both E) A192 and F) V2A192.