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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Cancer Res. 2014 Dec 12;75(3):605–614. doi: 10.1158/0008-5472.CAN-14-2527

Figure 1.

Figure 1

Soft tissue sarcomas resembling undifferentiated pleomorphic sarcoma (UPS) or pleomorphic rhabdomyosarcoma (pRMS) arise in P7KP mice following recombination with intramuscular (IM) 4-hydroxytamoxifen (4OHT). A) Representative sections are shown for sarcomas resembling UPS and pRMS. A hematoxylin and eosin (H&E) stained section is shown for each sarcoma subtype in addition to immunohistochemistry with antibodies directed against MyoD and myogenin. B) Histologic distribution of sarcomas in P7KP mice treated with IM 4OHT.