Scheme 1.
Synthetic schemes of acid valve assembly and incorporation of targeting agent. NVMSN denote particles that are modified with nanovalve only, and Tf-NV-MSN are particles that have both transferrin and nanovalve derivatizations.
Synthetic schemes of acid valve assembly and incorporation of targeting agent. NVMSN denote particles that are modified with nanovalve only, and Tf-NV-MSN are particles that have both transferrin and nanovalve derivatizations.