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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Oct 11;90(5):1143–1152. doi: 10.1016/j.ijrobp.2014.08.354

Table 2.

Toxicities during radiation.

Pt # Primary site RT (GyRBE) CSI (GyRBE) Concurrent chemo Toxicity during RT*
1 9 VCR, triple IT Death due to sepsis (5)
2 32.4 Etoposide
3 45 CYC, etoposide, VCR, triple IT Neutropenia (3)
4 21.6
5 50.4
6 54 CDDP, CYC, etoposide
7 50.4
8 52.2
9 45 23.4
10 54 Etoposide
11 50.4 30.6 Bevacizumab, irinotecan Sepsis (4), emesis (3)
12 50.4
13 50.4
14 54 CDDP, CYC, etoposide
15 50.4 IT depocyt, carbo
16 50.4
17 45 Carbo, IT MTX
18 52.2
19 54
20 54 36 Neutropenia (3)
21 51 24 Etoposide
22 54 36 Pancytopenia (3)
23 54 23.4
24 54 36 Pancytopenia (4)
25 55.8 23.4
26 54 30.6 Triple IT, ICE Pancytopenia (4)
27 54 30.6
28 43.2 36 Thrombocytopenia (4), hypertension (4)
29 55.8 23.4
30 54 23.4 Vononistat, accutane Anemia (3)
31 55.8 23.4
*

Grade 3 – 5 per RTOG Acute Radiation Morbidity Scoring Criteria. Grade of each toxicity shown in parentheses.

Pt, Patient; RT, radiation therapy; GyRBE, cobalt-Gray equivalent; VCR, vincristine; CDDP, cisplatin; CYC, cyclophosphamide; MTX, methotrexate; ICE, ifosfamide, carbo, etoposide; IT, intrathecal; carbo, carboplatin