. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Oct 11;90(5):1143–1152. doi: 10.1016/j.ijrobp.2014.08.354

Table 3.

Patients with radiographic and clinical evidence of radiation reaction

Pt #	Age at RT (m)	Surgery	Chemo before RT	Chemo with RT	Location of tumor bed	Location of imaging changes	Time to imaging changes after RT end (m)	Clinical signs concerning for RT reaction^*	Brainstem dose (GyRBE)
Pt #	Age at RT (m)	Surgery	Chemo before RT	Chemo with RT	Location of tumor bed	Location of imaging changes	Time to imaging changes after RT end (m)	Clinical signs concerning for RT reaction^*	Mean	Max
5	11	GTR	Yes	No	PF	Pons, medulla	4	Ataxia (3), hypotonia (3)	52.0	55.5
7	15	STR	Yes	No	PF	Brainstem, bilateral thalami, cerebellum	4	Ataxia (2)	47.2	53.2
12	19	STR	Yes	No	Left hemisphere	Pons, midbrain, bilateral hemsipheres	3	Quadraplegia (3) bulbar palsies (4)	28.7	52.8
13	19	GTR	Yes	No	Foramen of Monroe	Basal ganglia, midbrain	4	Hemiparesis (3) bulbar palsies (4)	20.1	51.3
\|22	42	GTR	Yes	No	PF	Pons	1	Unknown	48.5	56.4

Grade per CTCAE v4.0 shown in parentheses.

Pt, Patient; RT, radiation therapy; PF, posterior fossa; m, months; GTR, gross total resection; STR, subtotal resection