Table 1.

Effect of Holothuria arenicola extract on liver function enzymes and total protein level in serum of BDL rats

Parameters	Time period	Groups			% of improvement
		Sham	BDL	HaE
ASAT (IU/L)	7	149.70 ± 9.57b	191.55 ± 5.87c	147.25 ± 7.82b	29.59
	14	143.14 ± 9.08b	208.25 ± 10.02c	145.35 ± 10.4b	43.94
	28	144.90 ± 8.63b	262.85 ± 7.93d	150.02 ± 5.64b	77.86
ALAT (IU/L)	7	55.51 ± 0.99a	77.31 ± 5.39b	71.65 ± 4.27b	10.20
	14	54.18 ± 1.2a	103.86 ± 2.62c	67.95 ± 2.75b	66.27
	28	55.52 ± 1.1a	110.35 ± 5.25c	71.05 ± 5.45b	70.15
Serum total protein (mg/100 ml)	7	4.11 ± 0.46a	12.62 ± 0.5c	10.5 ± 1.47b	51.58
	14	4.15 ± 0.5a	14.86 ± 2.91b	12.95 ± 1.54bc	41.68
	28	4.17 ± 0.51a	15.42 ± 1.89bc	13.43 ± 0.84bc	47.72
Serum albumin content (g/100 ml)	7	5.51 ± 0.32c	2.81 ± 0.15a	3.51 ± 0.52ab	14.42
	14	5.86 ± 0.33c	3.84 ± 0.39ab	4.50 ± 0.22b	11.43
	28	6.1 ± 0.22c	2.63 ± 0.47a	6.30 ± 0.08c	60.16

Data are means ± SEM of six rats in each group.

Unshared letters between groups are the significance values at p < 0.05.