Table 3.
Influence of different NaHCO3 concentration on minimal inhibitory concentration (MIC) of selected strains
| Ceftazidime | Cefepime | Ertapenem | Meropenem | Imipenem | Doripenem | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Concentration of NaHCO3 (mmol/L) | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 |
| Strain nr. | ||||||||||||||||||||||||
| OXA_N3 | 0.5 | ≤0.5 | 0.5 | ≤0.5 | 1 | ≤0.5 | ≤0.5 | ≤0.5 | 8 | 32 | >32 | >32 | 2 | 4 | 16 | >32 | 4 | 0.5 | ≤0.5 | 2 | 1 | 1 | 8 | 16 |
| OXA_C3 | 4 | 1 | 4 | 4 | 16 | 2 | 1 | 1 | 1 | 16 | 32 | >32 | ≤0.5 | 2 | 4 | 8 | ≤0.5 | ≤0.5 | 1 | ≤0.5 | ≤0.5 | 1 | 2 | 2 |
| KPC_C1 | >32 | >32 | >32 | >32 | 16 | 16 | 32 | 16 | >32 | >32 | >32 | >32 | 8 | 32 | >32 | >32 | 8 | 8 | 8 | 2 | 4 | 8 | 16 | 8 |
| VIM_C2 | >32 | 16 | 16 | 16 | 32 | 16 | 16 | 8 | 4 | 32 | >32 | >32 | 1 | 8 | 8 | 8 | 1 | 1 | 1 | ≤0.5 | 2 | 2 | 2 | 2 |
| NDM_B1 | >32 | >32 | >32 | 16 | >32 | 32 | 32 | 4 | 16 | >32 | >32 | 16 | 4 | 32 | 32 | 4 | 2 | 8 | 2 | 0.5 | 8 | 16 | 16 | 2 |
| DHA_C3 | >32 | >32 | >32 | >32 | 2 | 2 | 2 | 2 | 8 | >32 | >32 | >32 | 2 | 8 | 16 | 4 | 2 | 8 | 16 | 1 | 1 | 2 | 4 | 0.5 |
| SHV_C2 | >32 | 32 | 16 | 4 | >32 | >32 | >32 | 16 | >32 | >32 | >32 | 32 | 4 | 4 | 4 | 4 | 1 | 1 | 1 | ≤0.5 | 2 | 2 | 2 | ≤0.5 |