Table 3.
Influence of different NaHCO3 concentration on minimal inhibitory concentration (MIC) of selected strains
Ceftazidime | Cefepime | Ertapenem | Meropenem | Imipenem | Doripenem | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Concentration of NaHCO3 (mmol/L) | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 | 0 | 12.5 | 25 | 50 |
Strain nr. | ||||||||||||||||||||||||
OXA_N3 | 0.5 | ≤0.5 | 0.5 | ≤0.5 | 1 | ≤0.5 | ≤0.5 | ≤0.5 | 8 | 32 | >32 | >32 | 2 | 4 | 16 | >32 | 4 | 0.5 | ≤0.5 | 2 | 1 | 1 | 8 | 16 |
OXA_C3 | 4 | 1 | 4 | 4 | 16 | 2 | 1 | 1 | 1 | 16 | 32 | >32 | ≤0.5 | 2 | 4 | 8 | ≤0.5 | ≤0.5 | 1 | ≤0.5 | ≤0.5 | 1 | 2 | 2 |
KPC_C1 | >32 | >32 | >32 | >32 | 16 | 16 | 32 | 16 | >32 | >32 | >32 | >32 | 8 | 32 | >32 | >32 | 8 | 8 | 8 | 2 | 4 | 8 | 16 | 8 |
VIM_C2 | >32 | 16 | 16 | 16 | 32 | 16 | 16 | 8 | 4 | 32 | >32 | >32 | 1 | 8 | 8 | 8 | 1 | 1 | 1 | ≤0.5 | 2 | 2 | 2 | 2 |
NDM_B1 | >32 | >32 | >32 | 16 | >32 | 32 | 32 | 4 | 16 | >32 | >32 | 16 | 4 | 32 | 32 | 4 | 2 | 8 | 2 | 0.5 | 8 | 16 | 16 | 2 |
DHA_C3 | >32 | >32 | >32 | >32 | 2 | 2 | 2 | 2 | 8 | >32 | >32 | >32 | 2 | 8 | 16 | 4 | 2 | 8 | 16 | 1 | 1 | 2 | 4 | 0.5 |
SHV_C2 | >32 | 32 | 16 | 4 | >32 | >32 | >32 | 16 | >32 | >32 | >32 | 32 | 4 | 4 | 4 | 4 | 1 | 1 | 1 | ≤0.5 | 2 | 2 | 2 | ≤0.5 |