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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Clin Perinatol. 2014 Nov 28;42(1):105–117. doi: 10.1016/j.clp.2014.10.008

Table 1.

Variation in the cumulative incidence of definite invasive candidiasis among placebo recipients in recent clinical trials of antifungal prophylaxis among premature infants.

Study Year Patient Population (Birth Weight, Age) Patients (N) Cumulative Incidence of Invasive Candidiasis Patients, Birth Weight <750 g (n) Cumulative Incidence of Invasive Candidiasis, Birth Weight <750 g
Kicklighter et al.24 2001 <1500 g, 0–28 days N=50 0% n=10 0%
Kaufman et al.25 2001 <1000 g, 0–42 days N=50 20% n=24 25%
Manzoni et al.45 2007 1000–1500 g, 0–30 days
<1000 g, 0–45 days
N=106 13% n=18 17%
Parikh et al.46 2007 <1500 g, 0–28 days N=60 25% n=0 -
Benjamin et al.44 2014 <750 g, 0–42 days N=173 7% n=173 7%