Table 1.

Cardiac function with E-domain peptide eluting MRS and empty MRS treatments in mice at 2 wks post-MI. Pressure-volume loop measurements in the closed chest configuration. HR-heart rate (beats per minute), MAP-mean arterial pressure (mmHg), ESP-end-systolic pressure (mmHg), EDP-end-diastolic pressure (mmHg), ESV-end systolic volume (μl), EDV-end diastolic volume (μl), SV-stroke volume (μl), CO-cardiac output (μlmin), CI-cardiac index (μl/min/g), EF-ejection fraction (%), SW-stroke work (mmHg/μl), dP/dt_max-maximum first derivative of change in systolic pressure with respect to time (mmHg/sec), dP/dt_min-maximum first derivative of change in diastolic pressure with respect to time (mmHg/sec), Tau-Glantz-time constant of fall in ventricular pressure by Glantz method (msec), MaxPower-maximum power (mWatts), TPR-total peripheral resistance (mmHg/μl/min).

Group Parameter	2 wk Sham	2 wk MI	MI+Epeptide MRS	MI+MRS	MI+Epeptide
HR	472±8.8	488±11.5	504.8±16.7	490.5±11.5	488.7±10.4
MAP	50±3.7	54.3±3	58±2.2	54.3±3	50.5±2.7
ESP	72.1±5.2	75.3±5.9	82.5±3	76±3.8	72±4.2
EDP	1.67±0.1	11.5±1.6^*	9.5±1.6^*	10.74±2.3^*	7.4±2.5^*
ESV	35.6±2.5	20.6±3.9^*	17.5±2.5^*	28.7±5	18.3±4.5^*
EDV	61.2±3	37.2±7^*	40.0±2.6^*	40.9±5.4^*	34.7±4.7^*
SV	25.6±1.2	16.2±3.1 ^*	23.5±1.7	20.3±1.8	16.6±3^*
CO	11602.4±335.6	7799.2±545	11852.2±931.3^†	10055.9±1094.7	8038.3±1494.6
CI	151.7±5	126.7±8	146±9.8	123.5±10.6	140±14.7
EF	42±1.7	42.1±2.6	58.3±4.3	43.6±4.8	48.4±8.5
SW	2082.8±199.6	1029±229.6^*	1678.3±215	1092.7±177^*	1072.5±223.8^*
dP/dt_max	4015.8±523.7	4581.5±583	5573±420.8	4705±510	4447.5±525.6
dP/dt_min	-4444.5±599	-4734.8±726	-5783.9±363	-4769.4±491	-4812.1±560.8
Tau-G	11.7±0.75	10.7±1.4	8.8±0.6	9.9±0.8	9.4±0.4
MaxPower	188947.7±42581	227440±52738	334165±36405.2	270026±42412.6	229866±37517.7
TPR	4.2±0.4	5.9±0.6	5.2±0.65	5.7±0.7	5.3±0.3

P<0.05 vs. Sham,

^†

P<0.05 vs. 2 wk MI (n=7-8 per group).