Table 1.

Screening tests for potentially transmissible infectious pathogens in donors and recipients undergoing fecal microbiota transplantation

Pathogen/Infection	Usual Tests	Recipient, Donor, or Both	Part of Routine or Extended Screening
Hepatitis A/B/C	Serum antibodies; serum PCR	Both	Routine
HIV	Third- or fourth-generation serum ELISA; serum RNA PCR if recent seroconversion possible	Both	Routine
Syphilis	Nontreponemal serum test followed by treponemal confirmatory test if positive (eg, serum RPR followed by TP-PA)	Both	Routine
Enteric bacterial pathogens (Salmonella species, E coli, Shigella species, and others)	Routine stool culture	Donor	Routine
Enteric helminths and protozoa	Stool microscopy for ova and parasites; antigen ELISAs for Giardia and Cryptosporidium species	Donor	Routine
Clostridium difficile	Stool EIA for bacterial products and/or PCR	Donor	Routine
Epstein-Barr virus	Serum antibodies; PCR	Both	Extended (HSCT and SOT patients)
Cytomegalovirus	Serum antibodies; PCR	Both	Extended (HSCT and SOT patients)
Others (Helicobacter pylori, HTLV, and many others)	Various tests	Usually donor only	Extended (research protocols)