Table 2.

Proposed contraindications to donation for fecal microbiota transplantation

Risk Factor/Condition	Absolute or Relative Contraindication
Known HIV or viral hepatitis infection or recent exposure (12 mo)	Absolute
High-risk sexual behaviors (sexual contact with someone infected with HIV/viral hepatitis, men who have sex with men, sex for money)	Absolute
Use of illicit drugs	Relative (can consider if in remission and in distant past)
Recent tattoo or body piercing (12 mo)	Relative
Incarceration or history of incarceration	Relative
Risk factors for Creutzfeldt-Jakob disease	Absolute
Recent travel (6 mo) to regions where endemic diarrheal illness is prevalent	Relative
Past or present irritable bowel syndrome, inflammatory bowel disease, or gastrointestinal malignancy/known polyposis	Absolute
Recent antibiotic use (3–6 mo or more)	Absolute (consider delaying FMT if able and another donor unavailable)
Ingestion of allergen with known recipient allergy (eg, tree nuts)	Relative (delay FMT if recent ingestion and donor abstains)
Others (eg, metabolic syndrome, major gastrointestinal surgery [such as gastric bypass], systemic autoimmune disease, atopic disorders [asthma, eczema, eosinophilic disorders of the gastrointestinal tract])	Relative/unknown