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. 2015 Jan 24;12(1):2. doi: 10.1186/2045-8118-12-2

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© Silverberg et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effects of cisternal kaolin injection. (A) At 10 weeks post-kaolin injection, there is marked histiocytic and granulomatous inflammation composed of many macrophages filled with kaolin in the SAS at the base of the brain (here around the hypothalamus and 3rd ventricle). (B) At six months post-kaolin injection, the inflammation has subsided leaving scarring and blockage in the SAS (below the 3rd ventricle) and a few small collections of histiocytes in the ventricle walls, here the 3rd ventricle (arrow). Masson trichrome stain, ×200.