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. 2015 Jan 24;12(1):2. doi: 10.1186/2045-8118-12-2

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© Silverberg et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Oligomeric Aβ immunoreactivity is intraneuronal. Top row: hippocampal NeuN (A) and oligomeric Aβ (B) immunoreactivity in a six-month-old tgAPP21 rat at 10 weeks post-kaolin showing a strong overlap of immunopositive neuronal cell bodies (C), ×400. Bottom row: Frontoparietal cortical NeuN (D) and oligomeric Aβ (E) immunoreactivity in a six-month-old tgAPP21 rat at 10 weeks post-kaolin also reveals a widespread concomitance of immunopositive neuronal cell bodies (F), ×200.