Table 3.
Functional annotation of the differentially expressed genes in domestic versus wild silkworms
| Gene name | Best BLAST hit in nr database; putative function | E-value | Microarray probe |
|---|---|---|---|
| BGIBMGA001622 | Uncharacterized protein | 6E-54 | sw21843 |
| BGIBMGA009199 | Organic cation transporter protein-like; excretion of endogenous compounds and xenobiotics [22] | 0.0 | sw15503 |
| BGIBMGA006745 * | laccase 2A; immune response and/or detoxification [23,24] | 0.0 | sw12993 |
| BGIBMGA014208 | Cytochrome b5; electron transfer component in a number of oxidative reactions [25] | 2E-84 | sw03099 |
| BGIBMGA010477 | Scavenger receptor class B member 4; absorption of carotenoid [26] | 0.0 | sw01562 |
| BGIBMGA002958 | Dopa decarboxylase 2; immune response [27] | 0.0 | sw15376 |
| BGIBMGA010553 | Putative fatty acyl-CoA reductase | 2E-58 | |
| BGIBMGA002577 * | Peroxisomal acyl-coenzyme A oxidase 1-like | 0.0 | |
| BGIBMGA002578 * | Peroxisomal acyl-coenzyme A oxidase 1-like | 0.0 | sw22703 |
| BGIBMGA010516 * | Glucose dehydrogenase [acceptor]-like | 0.0 | |
| BGIBMGA009925 * | Glucose dehydrogenase [acceptor]-like | 0.0 | sw21310 |
| Novel00011 | No hits | ||
| BGIBMGA009799 * | Aldose reductase-like isoform X1 | 0.0 | sw19860 |
| BGIBMGA006180 * | Venom dipeptidyl peptidase 4-like isoform X2; immune response [28] | 0.0 | sw14578 |
| Novel00061 | No hits | ||
| Novel01220 | Serine protease inhibitor 16 precursor; immune response [29] | 3E-37 | |
| Novel00917 | No hits | ||
| Novel00523 | Uncharacterized protein | 2E-63 | |
| Novel00365 | No hits | ||
| BGIBMGA004037 | Hypothetical protein EAG_07492 | 1E-10 | sw04615 |
| Novel00815 | Putative pol-like protein | 4E-52 | sw21903 |
| BGIBMGA003541 | Hypothetical protein KGM_18541 | 3E-169 | sw22611 |
| Novel01049 | Ubiquitin-like modifier-activating enzyme 5; to activate and transfer ubiquitin to ubiquitin conjugating enzymes [30] | 0.0 | sw12010 |
| BGIBMGA000013 | Osiris 9A | 1E-96 | sw13441 |
| BGIBMGA013131 | Apolipoprotein D-like; transporting lipids and other small hydrophobic molecules for metabolism [31] | 1E-154 | sw15906 |
| BGIBMGA014207 | Cytochrome b5; electron transfer component in a number of oxidative reactions [25] | 3E-90 | sw08853 |
| BGIBMGA007397 | Protein charybde-like | 8E-78 | sw03416 |
| BGIBMGA013477 | Synaptic vesicle glycoprotein 2B-like isoform X1; regulating excretion of proteins [32,33] | 0.0 | sw21450 |
| BGIBMGA009572 | Protein translocase subunit secA; protein export[34] | 0.0 | |
| BGIBMGA000776 | Juvenile hormone esterase-like | 0.0 | |
| BGIBMGA010386 | Non-lysosomal glucosylceramidase-like; glucosylceramide degradation pathway [35] | 0.0 | sw07262 |
| BGIBMGA009095 | Fungal protease inhibitor F-like isoform X1; immune response [29] | 2E-53 | sw01309 |
Up-regulated genes in the domestic strains are shown in bold; up-regulated genes in the wild silkworms are in normal font. *Genes related to oxidoreductase activity in the GO molecular function category. The microarray probes are from Xia et al. [11].