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. 2014 Dec 22;7(2):125–126. doi: 10.15252/emmm.201404815

Figure 1. Metabolic modulators enhance selective autophagy.

Figure 1

Both CBZ and MET activate AMPK by perturbing mitochondrial function. The result of these effects is an enhancement of selective autophagy, which can both kill intracellular bacteria and alter cytokine secretion from phagocytes.