Figure 3.

Comparison of positive tumor ratios between methods. Each data point represents two positive tumor ratios of the same case, rated by the same pathologist, using two methods. Solid diagonal lines mark complete agreement. Dotted lines denote 10% cutoff and isolate the discordant ratings in the upper left and lower right quadrant. (A) compares the microscopic method with virtual microscopy, and (B) compares virtual microscopy with assisted virtual microscopy. (C) How well the pathologists were able to estimate the positive tumor ratios of the outline sketches they had drawn, compared with their calculated ratios (Pearson's correlation coefficient was 0.974, P < 0.001.) Linear regression (dashed line) shows that positive tumor ratios were systematically overestimated.