Table 4.
Intraobserver agreements, comparing two rating methods
| Agreement of positive tumor ratio | Agreement of staining intensity | |||
|---|---|---|---|---|
| Methods compared | OCCC | Pearson's correlation coefficient | Number of disagreements | Kappa |
| Microscopy versus virtual microscopy | 0.647 | 0.651 (P < 0.001) | 20 | 0.505 ± 0.068 (P < 0.001) |
| Plain virtual microscopy versus virtual microscopy with area outlining assistance | 0.634 | 0.655 (P < 0.001) | 18 | 0.509 ± 0.067 (P < 0.001) |
| Microscopy versus virtual microscopy with area outlining | 0.665 | 0.680 (P < 0.001) | 18 | 0.551 ± 0.066 (P < 0.001) |
Agreements of positive tumor ratio were compared using OCCC, Pearson's correlation coefficient, and the number of discordant ratings with respect to the 10% cutoff. Agreements of staining intensities were calculated as kappa values.