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. 2014 Dec 10;4(2):253–267. doi: 10.1002/cam4.354

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© 2014 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Differential expression of resistance-related genes in carboplatin short-term-treated A2780 and A2780cis tumors identified by linear model analysis. (A) Schematic view of linear model analysis for identification of resistance-related genes. (B) Heat map of differentially expressed genes determined by Illumina bead chip array. Genes showing RNA fold change >twofold in carboplatin-treated A2780 and vehicle-treated A2780cis tumors compared to vehicle-treated A2780 tumors. (C) qRT-PCR analysis of GDF15, DRAM1, SULF2, P4HA2, and LMNA expression.