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Correlation between tumor ascorbate concentrations and levels of HIF-1 pathway members
| Tumor | n | Correlation | P 3 |
|---|---|---|---|
| HIF-1α1 | |||
| B16-F10 | 30 | −0.87 | <0.01 |
| LL/2 | 30 | −0.83 | <0.01 |
| GLUT-11 | |||
| B16-F10 | 30 | −0.46 | 0.04 |
| LL/2 | 30 | −0.56 | <0.01 |
| CA-IX1 | |||
| B16-F10 | 30 | −0.54 | <0.01 |
| LL/2 | 30 | −0.71 | <0.01 |
| VEGF2 | |||
| B16-F10 | 28 | −0.62 | <0.01 |
| LL/2 | 28 | −0.49 | 0.02 |
Relative protein level according to densitometry reading (details in methods).
Protein levels measured by ELISA.
Significance, two-tailed.
