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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Xenotransplantation. 2014 Sep 11;22(1):32–47. doi: 10.1111/xen.12133

Table 1.

Xenograft recipients and immunosuppressive therapy

Group Recipients ID Graft Survival (days) Immunosuppressive Therapy(a)
Organ xenotransplantation (n=7) Heart (n=3) B27104
B26704
B16107
GTKO
GTKO
GTKO/CD46
56
35
26
Kidney (n=4) B4207
B4307
B26904
B16307
GTKO/CD46
GTKO/CD46
GTKO
GTKO/CD46
9
10
6
10
Anti-CD154mAb + ATG + MMF
Pig artery patch xenotransplantation (n=8) n=3 B26504
B7506
B4007
GTKO
GTKO
GTKO
95
14*
29
None (b)
n=2 B7906
B3707
GTKO
GTKO
32
29
Anti-CD154mAb + ATG + MMF
n=3 B18408
B18608
B18208
GTKO
GTKO
GTKO
33
29
29
CTLA4-Ig + ATG + MMF
(a)

For details of dosages, see Supplementary Table 1.

(b)

Recipients stated to have no IS received cobra venom factor and methylprednisolone only on days −1, 0, and 1

ATG = Anti-thymocyte globulin / MMF = Mycophenolate mofetil

*

Euthanasia on day 14 due to rupture of patch graft.